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Sleeping Aids
The most common prescription Sleeping aids approved for use in treating insomnia are listed below: benzodiazepines (for example temazepam, estazolam,and others); the newer, non-benzodiasepines (for example zolpidem (Ambien,Ambien CR), Zaleplon (Sonatal), and eszopiclone (Lunesta); and the melatonin receptor agonist ramelteon (Rozerem).
These three Sleeping aids perform best once the people who are treated for insomnia are diagnosed with a physician and follow up treatment methods are regular. It is not uncommon by using these medications, some type of therapy may be required. For instance, Sonata includes a one hour amount of action, therefore it can be used as middle-of-the night awakenings. Giving the relatively level "therapeutic playing field" among the hypnotic sleeping aids, the cost towards the patient should be considered when selecting a medicine. Obviously, the list of approved medications in the patient's health plan much be looked at.
The medications usually have a minimal incidence of negative effects, along with a low abuse potential. For example, according to a published study in the American journal of Medicine in 1996 in which they analyzed various outcomes in 170 adult patients with long-standing sleep-disruptive disorders who were given nightly benzodiazepine therapy (usually clonazepan) not less than 6 months, and often for many years. Of these patients, 146 (86 percent discovered that this therapy completely or substantially controlled their sleep issues, 8 percent had negative effects (for example morning sedation ) requiring Sleeping aids changes, 2 percent had relapses of alcohol or chemical abuse requiring hospitalization, and 1 % at times misused their medications. Other less frequent side effects include morning, "hangover", dizziness, issues with balance, memory, or confusion.
Zolpidem, zaleplon, and eszopiclone are imidazopyridine medications that connect to a benzodiazepine receptor within the brain. Their advantages are rapid absorption, insufficient active metabolites, and low risk for side effects or abuse. Zolpidem has been extensively studied, with an excellent therapeutic profile during nightly use for approximately 6 months, although within our experience it can be used safely on a nightly bsis for more than a year in patients who are carefully followed. The usual dose is 5-10 mg. at night, with doses with doses of 15-20 mg at times getting used. Zaleplon is definitely an ultra-short-acting agent that is good at promptly restoring sleep in patients having issues with nocturnal awakenings. The usual dose is Two or three mg at bedtime.
